Preservation of Axillary Lymph Nodes Compared with Complete Dissection in T1-2 Breast Cancer Patients Presenting One or Two Metastatic Sentinel Lymph Nodes: The SINODAR-ONE Multicenter Randomized Clinical Trial
Articolo
Data di Pubblicazione:
2022
Abstract:
The SINODAR-ONE trial is a prospective noninferiority multicenter randomized study aimed at assessing the role of axillary lymph node dissection (ALND) in patients undergoing either breast-conserving surgery or mastectomy for T1-2 breast cancer (BC) and presenting one or two macrometastatic sentinel lymph nodes (SLNs). The endpoints were to evaluate whether SLN biopsy (SLNB) only was associated with worsening of the prognosis compared with ALND in terms of overall survival (OS) and relapse.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Axilla; Female; Humans; Lymph Node Excision; Lymph Nodes; Lymphatic Metastasis; Mastectomy; Neoplasm Recurrence, Local; Prospective Studies; Sentinel Lymph Node Biopsy; Breast Neoplasms; Sentinel Lymph Node
Elenco autori:
Tinterri, Corrado; Gentile, Damiano; Gatzemeier, Wolfgang; Sagona, Andrea; Barbieri, Erika; Testori, Alberto; Errico, Valentina; Bottini, Alberto; Marrazzo, Emilia; Dani, Carla; Dozin, Beatrice; Boni, Luca; Bruzzi, Paolo; Fernandes, Bethania; Franceschini, Davide; Spoto, Ruggero; Torrisi, Rosalba; Scorsetti, Marta; Santoro, Armando; Canavese, Giuseppe
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