Polymorphism of immunoglobulin enhancer element HS1,2A: allele *2 associates with systemic sclerosis. Comparison with HLA-DR and DQ allele frequency
Articolo
Data di Pubblicazione:
2007
Abstract:
To investigate the relationship of the polymorphic enhancer HS1,2 central to the 3' enhancer complex regulatory region (IgH3'EC) of the immunoglobulin heavy chain genes with systemic sclerosis (SSc) disease and compare it with HLA-DR and DQ associations.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Adult; Aged; Autoantibodies; Esophagus; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; HLA-DQ Antigens; HLA-DR Antigens; Humans; Immunoglobulin Heavy Chains; Male; Middle Aged; Phenotype; Scleroderma, Systemic; Statistics, Nonparametric; Stomach; Enhancer Elements, Genetic; Polymorphism, Genetic
Elenco autori:
Frezza, D; Giambra, V; Tolusso, B; De Santis, M; Bosello, S; Vettori, S; Triolo, G; Valentini, G; Ferraccioli, G
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