Combination of PPARg agonist pioglitazone and trabectedin induce adipocyte differentiation to overcome trabectedin resistance in myxoid liposarcomas
Articolo
Data di Pubblicazione:
2019
Abstract:
This study was aimed at investigating whether the PPARĪ³ agonist pioglitazone-given in combination with trabectedin-is able to reactivate adipocytic differentiation in myxoid liposarcoma (MLS) patient-derived xenografts, overcoming resistance to trabectedin.
Tipologia CRIS:
1.1 Articolo in rivista
Elenco autori:
Frapolli, Roberta; Bello, Ezia; Ponzo, Marianna; Craparotta, Ilaria; Mannarino, Laura; Ballabio, Sara; Marchini, Sergio; Carrassa, Laura; Ubezio, Paolo; Porcu, Luca; Brich, Silvia; Sanfilippo, Roberta; Casali, Paolo Giovanni; Gronchi, Alessandro; Pilotti, Silvana; D'Incalci, Maurizio
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