Ferroptosis‐Associated Fibroblast Activation and Transcriptional Remodelling in Human Heart Failure: A Proof‐of‐Concept Study
Articolo
Data di Pubblicazione:
2026
Abstract:
: Single-cell analysis of human heart failure identifies a fibroblast-enriched ferroptosis signature that distinguishes DCM from controls and reveals a pseudotime trajectory linking ferroptotic stress to progressive fibroblast activation and pro-fibrotic remodelling.
Tipologia CRIS:
1.7 Lettera
Elenco autori:
Karampinos, Konstantinos I.; Georgiopoulos, Georgios; Kallikourdis, Marinos; Gurung, Rijan; Foo, Roger; Cokkinos, Dennis V.; Farmakis, Dimitrios
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