IL-23 skin and joint profiling in psoriatic arthritis: novel perspectives in understanding clinical responses to IL-23 inhibitors
Articolo
Data di Pubblicazione:
2021
Abstract:
To determine the relationship between synovial versus skin transcriptional/histological profiles in patients with active psoriatic arthritis (PsA) and explore mechanistic links between diseased tissue pathology and clinical outcomes.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
arthritis; biological therapy; psoriatic; synovitis; Adult; Antirheumatic Agents; Arthritis, Psoriatic; Female; Gene Expression Profiling; Humans; Interleukin-17; Interleukin-23; Male; Middle Aged; Principal Component Analysis; Skin; Synovial Membrane; Synovitis; Treatment Outcome; Tumor Necrosis Factor Inhibitors; Ustekinumab
Elenco autori:
Nerviani, Alessandra; Boutet, Marie-Astrid; Tan, Wang Sin Gina; Goldmann, Katriona; Purkayastha, Nirupam; Lajtos, Tamas Ajtos; Hands, Rebecca; Lewis, Myles; Kelly, Stephen; Pitzalis, Costantino
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