Data di Pubblicazione:
2015
Abstract:
ELR+ CXC chemokines are heparin-binding cytokines signalling through the CXCR1 and CXCR2 receptors. ELR+ CXC chemokines have been associated with inflammatory arthritis due to their capacity to attract inflammatory cells. Here, we describe an unsuspected physiological function of these molecules in articular cartilage homeostasis.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Chemokines; Chondrocytes; Osteoarthritis; Animals; Apoptosis; Blotting, Western; Cartilage, Articular; Cells, Cultured; Chondrocytes; Disease Models, Animal; Homeostasis; Humans; Male; Mice; Mice, Inbred BALB C; Osteoarthritis; Receptors, Interleukin-8B; Signal Transduction
Elenco autori:
Sherwood, Joanna; Bertrand, Jessica; Nalesso, Giovanna; Poulet, Blandine; Pitsillides, Andrew; Brandolini, Laura; Karystinou, Alexandra; De Bari, Cosimo; Luyten, Frank P; Pitzalis, Costantino; Pap, Thomas; Dell'Accio, Francesco
Link alla scheda completa:
Pubblicato in: