L-asparagine depletion and L-asparaginase activity in children with acute lymphoblastic leukemia receiving i.m. or i.v. Erwinia C. or E. coli L-asparaginase as first exposure
Articolo
Data di Pubblicazione:
2000
Abstract:
The present study was aimed at investigating L-asparaginase (L-ASE) activity (in plasma) and L-asparagine (L-ASN) depletion (in plasma and CSF) in children with newly diagnosed acute lymphoblastic leukemia (ALL) exposed for the first time to different L-ASE products.
Tipologia CRIS:
1.1 Articolo in rivista
Keywords:
Antineoplastic Agents; Asparaginase; Asparagine; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Administration Schedule; Escherichia coli; Female; Follow-Up Studies; Humans; Injections, Intramuscular; Injections, Intravenous; Male; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Treatment Outcome
Elenco autori:
Rizzari, C; Zucchetti, M; Conter, V; Diomede, L; Bruno, A; Gavazzi, L; Paganini, M; Sparano, P; Lo Nigro, L; Aricò, M; Milani, M; D'Incalci, M
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